Vardenafil

Vardenafil is the most powerful inhibitor (blocker) of phosphodiesterase type 5, which stimulates stable and prolonged blood circulation in the corpus cavernosum, most of which are located in the genitals. Hence, it affects erection in men and an increase in groin sensitivity in women. Much more effective than sildenafil and tadalafil.

The duration of work is similar to Viagra (4-5 hours). The cardinal difference lies in the speed of the onset of action, with vardenafil you are ready to perform sexual feats at a new level 10-15 minutes after taking it. If you are interested in what price Vardenafil has, then it depends on dosage, as well as its constituent components and effectiveness. The doctor will tell you more.

What is Vardenafil

The whole essence of the action of vardenafil is to block the enzyme – PDE5, which does not allow the smooth muscles of the corpora cavernosa (penis) to relax. As soon as you take the pill, one natural inhibitory factor becomes less, and practically nothing interferes with the occurrence of an erection, except for your natural desire, without which it is impossible. Immediately it is worth dispelling the myth and fears of many beginners who think that having taken the pathogen, they will walk for several hours with a constant boner.

This is far from the case because blood circulation occurs only under the action of a nerve impulse that goes from the brain to the nervous processes in the cavernous bodies. As a result, nitric oxide is released and local tissue relaxation occurs, after which the vessels expand and the blood flow does not interfere with the filling of the genitals.

Diagnosis of erectile dysfunction

The symptoms of impotence are obvious, but for effective treatment, you need to determine the exact cause of the disease. To do this, when visiting a urologist, analyzing complaints, taking a patient’s anamnesis, a doctor’s examination is carried out. If necessary, prescribe laboratory or hardware studies (for example, ultrasound of the prostate gland).

Erectile dysfunction not only affects the psychological state of a man, worsening the quality of life, but it can be a sign of more dangerous pathologies, so sometimes doctors recommend other examinations, for example, computed tomography of the brain, abdominal organs, angiography, etc.

How to use

Like any other type 5 phosphodiesterase blocker, it is taken 20-30 minutes before the intended sexual intercourse with a moderate amount of water. Vardenafil is combined with alcohol and acts even better in combination, but the load on the heart also increases. If you have health problems, we strongly advise against combining the supplement with alcohol. It is important to adhere to the rules of admission, and Vardenafil without a prescription must be purchased only with the approval of the attending physician.

Pharmacodynamics

Vardenafil online blocks phosphodiesterase, which breaks down cyclic guanosine monophosphate, thereby increasing the action of endogenous nitric oxide in the corpus cavernosum during sexual stimulation, which determines the ability of vardenafil to enhance the natural response to sexual stimulation.

The clinical effect is realized even before reaching Cmax. After oral administration in doses of 20 mg and 10 mg, the effect occurs after 10 minutes, which provides an erection sufficient for penetration and successful completion of intercourse in 34% and 40% of patients with mild to moderate erectile dysfunction, respectively. After 25 minutes, the effect occurs in 53% and 50% of patients, respectively, which coincides in time with the onset of the appearance of the active substance in the blood and a rapid increase in its concentration. The duration of action is 8-12 hours.

Side effects of Vardenafil

Vardenafil is a drug with many years of practical experience in use all over the world. In addition, it has passed all stages of clinical trials and has long been sold in pharmacies and various online stores in different countries.

The most common contraindications for the use of Vardenafil are:

• dizziness (the most common sensation, manifested in 10-15% of cases, disappears after a few hours);
• blood filling of the facial skin (it happens in 5-10% of users, it has a purely external effect);
• nasal congestion (this is an unpleasant feeling in 3-5% of people);
• indigestion (the rarest side effect, occurs in 1-2%, is most often associated not with taking vardenafil, but with accompanying food that is poorly absorbed).
• headache, increased muscle tone, facial flushing, increased or decreased blood pressure, dyspepsia, nausea, nasal congestion, photosensitivity, priapism.

It is important to know: The above problems are of a short-term nature and disappear immediately after you stop taking the drug. However, it is still not recommended to buy Vardenafil without a doctor’s prescription.

Original and generics

The most popular drug based on the active ingredient Vardenafil is Levitra. Produced by the renowned German pharmaceutical company Bayer. Levitra is currently a registered trademark, the use of which is prohibited by the manufacturer’s copyright. Most often, tablets are small, round, dark orange in color, with characteristic embossed dosage numbers.

There are analogs, the so-called generics, which have exactly the same active ingredient, but are much cheaper. The main manufacturers of these drugs are located in India.

Despite this, it is easy to calculate that the benefits of buying an analog can be multiple. In addition, Levitra will not be sold just like that, because it is a prescription drug. Therefore, do not risk buying Vardenafil without a prescription online, as it will be illegal. 

Overdose

Symptoms: In studies of 8 healthy volunteers taking a single dose of up to 120 mg, most of them experienced reversible low back pain/myalgia and / or visual impairment. You can buy Vardenafil at any pharmacy or special online store.

Treatment: supportive therapy. Dialysis is not expected to be effective due to increased clearance. Vardenafil is characterized by a high degree of binding to blood plasma proteins and is not excreted in significant quantities in the urine. If you are still taking any medications, then remember that the interaction of Vardenafil with other medications is at a high level and does not harm your health.